He did a postdoctoral fellowship in developmental biology at UCSD where he researched the multiple differentiation paths of Dictyostelium discoideum.
His research into hereditary inheritance of traits outside of DNA was initially seen as controversial, and he was told that if he continued this work, his funding would be cut off.
[2] Dr. Feinberg discovered epigenetic alterations in human cancer with Bert Vogelstein in 1983.
[1] He has made many contributions to the field of epigenetics in cancer, and discovered the molecular basis of Beckwith-Wiedemann syndrome.
[2] He pursued this work while he was an HHMI Investigator at the University of Michigan from 1986-1994,[3] when he returned to Johns Hopkins as King Fahd Professor of Molecular Medicine in the Department of Medicine.