Thus, tissues which are very sensitive to oxygen levels, such as the retina, develop microangiopathy and may cause blindness (so-called proliferative diabetic retinopathy).
[5] Amyloid buildup causes brittle blood vessels, which can lead to lobar intracerebral hemorrhages (ICH).
In addition, hemosiderosis, inflammatory leukoencephalopathy, Alzheimer's disease, accidental microbleeds, cognitive deficits, and transitory neurological symptoms may manifest.
These deposits gradually harden and become more noticeable over time, restricting (stenosing) the artery and impairing normal blood flow.
Larger hemorrhages may result in greater focused deficits, headaches, seizures, speaking difficulties, and muscular weakness.
Treatment options for situations of muscle weakness may include speech, occupational, or physical therapy.
[8] Despite the fact that CAA does not appear to be primarily caused by hypertension, blood pressure reduction has also been linked to advantages in terms of mortality.
[9] Finally, a small body of research has demonstrated the advantages of using immunosuppression to treat the inflammatory forms of CAA.