Anne became queen when Richard acceded to the throne in June 1483, following the declaration that Edward IV's children by Elizabeth Woodville were illegitimate.

[3] With King Henry VI imprisoned in the Tower of London, the de facto Lancastrian leader was his consort, Margaret of Anjou, who was suspicious of Warwick's motives.

To quell these suspicions, Anne Neville was formally betrothed to the son of Henry VI and Margaret of Anjou, Edward of Westminster, at the Château d'Amboise in France.

She was taken first to Coventry and then to the house of her brother-in-law the Duke of Clarence in London, while her mother Anne Beauchamp, Warwick's wife, sought sanctuary in Beaulieu Abbey.

When the crisis settled down and the Countess wished to be restored to her estates, Edward IV refused her safe conduct to plead her case; she wrote to Queen Elizabeth and several others to no avail.

Clarence, anxious to secure the entire inheritance, treated her as his ward and opposed her getting married, which would strengthen her position to claim a share.

[4] The exact date of the wedding of Anne Neville and Richard, Duke of Gloucester, is not known, although most sources agree that a ceremony took place sometime in the late spring/early summer of 1472 in St Stephen's Chapel in the Palace of Westminster, after a dispensation to marry was issued from Rome on 22 April 1472.

[10] The couple made their marital home in the familiar surroundings of Middleham Castle, Yorkshire, after Richard was appointed Governor of the North on the king's behalf.

[11] Anne's mother, the Countess of Warwick, joined her daughter's household in 1473 after Richard obtained the king's permission to release his mother-in-law from her guarded sanctuary.

Anne Neville was crowned alongside her husband on 6 July 1483 by Thomas Bourchier, Archbishop of Canterbury, the first joint coronation in England in 175 years.

The queen's train was borne by Margaret, Countess of Richmond, whose son would become Henry VII after defeating Richard at the Battle of Bosworth.

[13][14] Richard and Anne's son, Edward of Middleham, was created Prince of Wales in York Minster on 8 September 1483 following their Royal Progress across England.

[15] Anne was on good terms with her mother-in-law Cecily Neville, Duchess of York, with whom she discussed religious works, such as the writings of Mechtilde of Hackeborn.

[18] After Anne Neville died, Richard may have named another nephew, John de la Pole, Earl of Lincoln, as his heir presumptive.

[23] Richard sent Elizabeth away from court to Sheriff Hutton and publicly rebutted these rumours on 30 March 1485 during an assembly of Lords he had summoned at the Hospital of St. John.

Addressing them "in a loud and distinct voice", he "showed his grief and displeasure aforesaid and said it never came into his thought or mind to marry in such manner wise, nor willing nor glad of the death of his queen but as sorry and in heart as heavy as man might be …".