Prior to 18 weeks' gestation, the fetal organs may be of insufficient size and development to allow for ultrasound evaluation.
Scans performed beyond 22 weeks' gestation may limit the ability to seek pregnancy termination, depending on local legislation.
These markers are often not clinically significant and do not cause adverse pregnancy outcomes, but used in order to decide whether additional tests, which will be more accurate, are needed.
However, performing an ultrasound for the sole purpose of determining fetal sex without a medical indication is not recommended.
These factors include the severity of the anomaly, the background risk of the study population, gestational age at time of scan, the expertise of the ultrasound technician and interpreting obstetrician, and maternal obesity.