Anonas station was opened on April 5, 2003, as part of the initial section of LRT Line 2 between Araneta Center–Cubao and Santolan.

Various educational institutions are located within a walking distance of the station, including but not limited to World Citi Medical Center and the Quezon City campus of the Technological Institute of the Philippines.

Buses and jeepneys ply the Anonas Street and Aurora Boulevard routes.

Commuters bound for Project 4 must use the southern exit to access Hi-Top Supermart and the National College of Business and Arts–Cubao.

A tricycle terminal can be seen near Hi-Top Supermart that will bring the commuters to their desired destinations.