In 1891, the schoolhouse at this site burned down, forcing classes to be relocated to another building for the remainder of the year.

"[8] Apopka High's accreditation was last renewed in 2010 by AdvancED: Southern Association of Colleges and Schools.

[16] Apopka competes in the Florida High School Athletic Association and has about 26 total sports teams.

[17][18][19] The Apopka High School football team competes in District 4, Region 1 of FHSAA Class 8A.

Darlington left Apopka after the 2018 season, and currently coaches football at DeLand High School.

[20] Apopka High School boys varsity bowling team had three consecutive undefeated seasons in 2013, 2014, and 2015.