One route of 12.96 miles (20.86 km) begins at US Highway 79 (US 79) near Stuttgart and runs east to the White River at Preston Ferry.

The route runs due east as a section line road, immediately crossing railroad tracks and intersecting with Highway 146 Spur.

The route continues east to the a boat ramp on the White River at Preston Ferry, where it terminates.

[4] Highway 146 begins at Resort Rd at Lawrenceville, on the banks of Maddox Bay and along the eastern limits of the White River National Wildlife Refuge.

The route begins at Highway 146 and runs southwest, parallel to US 79 into Stuttgart to a junction with US 165, where it terminates.

[12] Due to an expansion by the St. Louis Southwestern Railway, the roadway was obliterated and shifted onto new right-of-way on November 27, 1974.