One segment of 4.9 miles (7.9 km) begins east of the Ward Reservoir and runs north to the La Grue Bayou.

A second segment of 11.4 miles (18.3 km) runs from Morgan Loop Road south of Ethel north to Highway 1 at St. Charles.

A third segment of 21.8 miles (35.1 km) runs from Highway 1 at Cross Roads north to U.S. Route 79 (US 79) at Park Grove.

The route begins at Morgan Loop Road south of Ethel and runs north for about 11.4 miles (18.3 km) until it reaches the intersection of Highway 1 in St. Charles, where it terminates.

Between Brinkley and Cotton Plant, the route is designated as the "Sister Rosetta Tharpe Memorial Highway".