A third route was dedicated in May 2013 [3] and begins at State Line Avenue in Texarkana and continues east to Interstate 49 (I-49)/US 71.

Highway 151 begins at US 78/Highway 18 (Main Street) in Blytheville and runs north to Gosnell and Arkansas International Airport.

[4] The route intersects and forms a concurrency with Highway 181 northwest for 2.04 miles (3.28 km), with Highway 151 splitting north to terminate at Missouri supplemental route TT at the Missouri state line.

This 1.4 miles (2.3 km) section is an extension of Loop 151 and was formerly signed Arkansas Highway 245.

The route was signed at the on-ramps from the Arkansas side of State Line Avenue with 151 shields and has no exits between its termini.