150) is a 14.19-mile-long (22.84 km) east–west state highway in Mississippi County, Arkansas.

[3] The highway has a spur route that serves as a shortcut to travelers looking for US 61 southbound and later intersects and begins a concurrency near Yarbro.

[2] After the concurrency ends, Highway 150 intersects Interstate 55 at exit 71.

150S) is a north–south state highway spur route at Yarbro.

The route of 0.45 miles (0.72 km) serves to connect travelers on Highway 150 to US 61 heading south.