The county is located in the Arkansas Delta, a flat alluvial plain known for fertile soils near the Mississippi River.

East of the bridge, Highway 312 terminates at an intersection with US 61 and the Great River Road.

[3] As of 2016, the route had an annual average daily traffic (AADT) of 1,700 vehicles per day (VPD).

[5] The highway runs due east as a section line road, passing over I-55 without an intersection before straddling the southern city limits.

[8] A third segment was created pursuant to Act 9 of 1973 by the Arkansas General Assembly.