[4] It is on the eastern border of the state in the Arkansas Delta, formed by the lowlands of the Mississippi River.

It was an area of large cotton plantations in the antebellum era, when the workers were enslaved African Americans.

On September 4, Paul M. Cobbs, a white Democrat, shot at men guarding the precinct ballot box and wounded seven.

[15] The Union Labor Party's gubernatorial and Arkansas's 1st congressional district candidates also won St. Francis County.

[17][18] A portion of St. Francis County is represented in the Arkansas State Senate by Republican Ronald R. Caldwell.

By the late 1960s, white conservatives began to shift into the Republican Party, and St. Francis County was carried by Richard Nixon in 1972 amidst a national landslide.

The county has voted Democratic in every subsequent presidential election, albeit be narrowing margins in recent years.

Each township includes unincorporated areas; some may have incorporated cities or towns within part of their boundaries.

However, the United States census does list Arkansas population based on townships (sometimes referred to as "county subdivisions" or "minor civil divisions").

Each town or city is within one or more townships in an Arkansas county based on census maps and publications.