[7] The far western portions of Cantrell Road in recent years have been the site for increased commercial development in Little Rock, including the controversial 2004 opening of a Wal-Mart Supercenter near upscale residential communities immediately south of the highway in Chenal Valley.

Cantrell Road runs with neighborhoods to the south and parks to the north, passing Arkansas Baptist High School.

[8] The highway intersects I-430 at a Parclo interchange and runs deeper into downtown Little Rock, passing numerous houses on the National Register of Historic Places.

[8] Cantrell Road continues past the Jackson Reservoir near the Cammack Village area, crossing University Avenue.

Even in 1926, however, US 64 was constructed to higher standards than Highway 10, making US 64 always the more feasible route for travelers from Fort Smith to the state capitol.

Highway 10 remains the "scenic path" from Fort Smith, passing through the Ouachita Mountains at a slower pace than the bustling four-lane freeway.