Arsenate reductase (azurin)

Arsenate reductase (azurin) (EC 1.20.9.1) is an enzyme that catalyzes the chemical reaction The 3 substrates of this enzyme are arsenite, water, and oxidised azurin, whereas its 3 products are arsenate, reduced azurin, and hydrogen ion.

This enzyme belongs to the family of oxidoreductases, specifically those acting on phosphorus or arsenic in donor with a copper protein as acceptor.

The systematic name of this enzyme class is arsenite:azurin oxidoreductase.

This enzyme is also called arsenite oxidase.

The enzyme contains a molybdopterin centre comprising two molybdopterin guanosine dinucleotide cofactors bound to molybdenum, a [3Fe-4S] cluster and a Rieske-type [2Fe-2S] cluster.