Note that in fields that commonly deal with groundwater chemistry, arsenite is used generically to identify soluble AsIII anions.
[1] A number of different arsenite anions are known: In all of these the geometry around the AsIII centers are approximately trigonal, the lone pair on the arsenic atom is stereochemically active.
[10] Arsenic in its trioxide, As2O3, (brand name Trisenox, ATO) is used as a chemotherapy drug against acute promyelocytic leukaemia (APL), a type of myeloid leukemia.
The researchers conjectured that historically these photosynthesizing organisms produced the arsenates that allowed the arsenate-reducing bacteria to thrive.
[14] In humans, arsenite inhibits pyruvate dehydrogenase (PDH complex) in the pyruvate-acetyl CoA reaction, by binding to the –SH group of lipoamide, a participant coenzyme.