Artificial butter flavoring

[2][3] Workers in several factories that manufacture artificial butter flavoring have been diagnosed with bronchiolitis obliterans, a rare and serious disease of the lungs.

NIOSH investigated the worksite and suggested that artificial butter flavoring containing diacetyl was the most likely causative agent for the cases of bronchiolitis obliterans.

The plant effectively implemented changes reducing air concentrations of diacetyl by 1 to 3 orders of magnitude in the years following.

[7] Additionally further studies have demonstrated a large increase in abnormal spirometry values in workers exposed to flavoring chemicals with a clear dose-response relationship.

[13] The notice requests respondents to provide input regarding adverse health effects, methods to evaluate and monitor exposure, the training of workers.

[24] Manufacturers of butter flavored popcorn including Pop Weaver, Trail's End, and ConAgra Foods (maker of Orville Redenbacher's and Act II) began removing diacetyl as an ingredient from their products.