A t(1;12)(q21;p13) translocation, which results in a TEL–ARNT fusion protein, is associated with acute myeloblastic leukemia.

The aryl hydrocarbon receptor (AhR) is involved in the induction of several enzymes that participate in xenobiotic metabolism.

The ligand-free, cytosolic form of the aryl hydrocarbon receptor is complexed to heat shock protein 90.

Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only into[verification needed] the nucleus.

Aryl hydrocarbon receptor nuclear translocator has been shown to interact with: This article incorporates text from the United States National Library of Medicine, which is in the public domain.