Between 1641 and 1642, Asalat Khan combated Raja Jagat Singh, as one of the Mughals' three commanders in a campaign against the kingdom of Nurpur; the rebellion was subdued.

In October 1645, Shah Jahan instructed Asalat Khan to recruit troops at Kabul, with the intention of using the city as a staging ground for the Central Asian campaigns.

Soon after military incursions and reconnaissance had started, Asalat Khan led a sixteen-day expedition over the Hindu Kush, seizing livestock and prisoners as retaliation for local rebellion.

[7] By July the Mughal army had reached Balkh and captured it with minimal resistance; however, its ruler Nazr Muhammad attempted to escape with his treasure.

[8][1][9] Asalat Khan died prematurely in the winter of 1647, while still stationed in Balkh for the ongoing Central Asian campaign, from exposure to cold conditions.

[2] Asalat Khan owned a haveli (residence) in Agra along the right bank of the Yamuna River, close to the Taj Mahal complex; the structure is not fully preserved.