The format of the series was very similar to the Marvel Team-Up comic book where Spider-Man teams up with another character in every issue.

[1] The first issue was released 9 November 2011, with Zeb Wells as the writer, Joe Madureira as the penciller, and Ferran Daniel as the colorist.

[6] The response to the free digital code in the first issue was so positive that Marvel announced they would include free digital codes in comic books in their Ultimate line of comics starting in January 2012.

[7] The free digital copy with purchase, still using the sticker to protect the code, was extended to the fifth, sixth, and seventh issues before all Marvel comics priced at $3.99 started receiving free digital codes in June 2012 (issue eight) due to the success of the free digital codes in Avenging Spider-Man and the Ultimate line of comics.

It would retain the creative team of writer Christopher Yost and artists Paolo Rivera and Marco Checchetto.