1T5I, 1T6N, 1XTI, 1XTJ, 1XTK791953817ENSG00000235439ENSG00000225859ENSG00000230624ENSMUSG00000019432Q13838Q9Z1N5NM_004640NM_080598NM_001252457NM_019693NP_004631NP_542165NP_001239386NP_062667Spliceosome RNA helicase BAT1 is an enzyme that in humans is encoded by the BAT1 gene.
[5][6][7] This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing.
The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm.
These genes are all within the human major histocompatibility complex class III region.
Alternatively spliced transcript variants encoding the same protein have been described.