[4] The results of this study showed that these proteins (p68, SrmB, MSS116, vasa, PL10, mammalian eIF4A, yeast eIF4A) involved in RNA metabolism had several common elements.
[5] There were nine common sequences found to be conserved amongst the studied species, which is an important criterion of the DEAD box family.
[13] There are three DEAD box proteins in the yeast system, Sub2, Prp28, and Prp5, which have been proven to be required for in vivo splicing.
The eIF4A translation initiation factor was the first DEAD box protein found to have an RNA-dependent ATPase activity.
[17] Ded1 is another DEAD box protein that is also needed for translation initiation, but its exact role in this process is still obscure.