The Battle of Suez occurred in 1541 and was a failed attack by the Portuguese against the Ottomans.

[4][5] In 1541 the Portuguese fleet under the command of the Portuguese governor of India Estêvão da Gama and his brother Cristóvão da Gama penetrated into the Red Sea.

[4] After sacking Suakin, the governor detached 16 light oarvessels and 250 picked men.

[2] The aim was to attack Suez but the attack was a failure as the heavy defence as well as the opposition of Davud Pasha and the Ottoman artillery forced the Portuguese to retreat.

[8] For the duration of the 1541 Suez campaign, the Portuguese remained within the Red Sea for seven months, never being confronted by the Ottoman navy, while Muslim trade was paralized.