The Belgian Health Care Knowledge Centre (abbreviated to KCE) is an independent federal research institute in Belgium that provides multidisciplinary scientific advice to relevant persons and authorities on topics related to health care.

Lastly, the KCE critically reviews, analyses, and summarizes publications from foreign research institutes and peer reviewed journals that could be of interest to Belgian clinicians and authorities.

[2] It was founded in 2003 and operates under the administrative authority of the Federal minister of Public Health of Belgium.

[3] Its annual budget is approximately 10,000,000 euros, and originates for about 75% from the National Institute for Health and Disability Insurance (NIHDI) and for about 25% from the Federal Public Service Health and the Federal Public Service Social Security.

Additionally, the KCE disposes over a budget of approximately 10,000,000 euros for its clinical trials programme, which fully originates from the NIHDI.