In 1940, with even further enrollment expansion, the school moved to its current location at 2900 Martin Luther King Jr. Drive.

In the 1960s and 1970s, as the population in Cleveland shifted and the costs of Catholic education rose, school enrollment shrunk.

The 1980s also brought about a capital campaign that sparked improvements in classrooms, and the building of a new church and bell tower.

Accreditation: To receive a diploma, students must earn 24 credits in college preparatory classes.

The school has an outstanding academic record, with recent graduates qualifying as National Merit semi finalists, a current Hesburgh Scholar at the University of Notre Dame, and as of 2014, the school boasted acceptance of at least one graduate into one or more of the U.S. military academies in sixteen of the last eighteen years.

The school has been met with success in baseball, basketball, football, hockey, track & field, lacrosse, & soccer.

Benedictine is the only school in Ohio to win an OHSAA State Championship in every decade since its inception.

Nearly 100% of graduates go on to college earning an average of over $5 million in scholarships, grants and financial aid overall.

Academic Challenge is a television game show in which high school teams answer questions to earn points and is broadcast on WEWS-TV.

Initiated in the spring of 2016 with a Robotics course and its first local engineer guest-speakers and design challenges, the department and club began at roughly the same time.

The band is made up of Benedictine high schoolers and girls from Beaumont School (Ohio).

The band goes to every varsity football game, and also marches in the Columbus Day Parade in Little Italy each October.

The club was moderated by Father Timothy Buyansky OSB who had directed shows at Benedictine for over 40 years.