Benzene 1,2-dioxygenase

In enzymology, a benzene 1,2-dioxygenase (EC 1.14.12.3) is an enzyme that catalyzes the chemical reaction The 4 substrates of this enzyme are benzene, NADH, H+, and O2, whereas its two products are cis-cyclohexa-3,5-diene-1,2-diol and NAD+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen.

The systematic name of this enzyme class is benzene,NADH:oxygen oxidoreductase (1,2-hydroxylating).

This enzyme participates in naphthalene and anthracene degradation.

It has 4 cofactors: FAD, Iron, Sulfur, and Iron-sulfur.