After several disagreements between the clubs of Biscay and Gipuzkoa, culminating in a pivotal championship match between Athletic and Real Sociedad being abandoned,[3] in 1918 the National Committee of the Spanish federation agreed to divide the Northern Federation in these two regions.
In 1922 the clubs in the province of Santander finally left the North Federation to create its own umbrella organisation, which launched the Cantabrian Regional Championship.
Five teams participated in the reborn Biscay Championship, including its winners Bilbao Athletic (a team formed by Athletic Bilbao, who decided not to use the club's official title as they only had a makeshift squad and were worried about embarrassing results tarnishing their reputation)[7] and runner-up Barakaldo Oriamendi, who both took part in the 1939 Copa del Generalísimo.
The last edition of the Championship of Biscay, which was also a qualifier for access to the 1940 Copa del Generalísimo, was played in the 1939–40 season.
Another restructuring approved by the Spanish Federation in 1940 marked the demise of the regional championships.