Blastoconidium

The next step is bud growth, a process that is regulated by the synthesis of new cellular components and turgor pressure created by the parental yeast cell.

The conditions at which this organism exists as a yeast (commensal) occur when the temperature is less than 30°C, pH is less than 7, serum is absent, and nitrogen is abundant.

The conditions at which this organism occurs as hyphae (pathogenic) are when the temperature is 37°C, pH is greater than 7, serum is present, and nitrogen is limiting.

Through a study conducted on Candida albicans, it was concluded that the blastoconidia produced a different cytokine profile that resulted in more of a host immune response.

This happens because blastoconidia produce adhesin proteins that facilitate and enable the yeast to attach to host cells.

Candida albicans budding to produce a blastoconidium
Cryptococcus neoformans yeast cells
Candida albicans pseudohyphae located at number 1