Several black students chose Blytheville High School to receive a college preparatory education.

In 1970, a federal court judge in nearby Jonesboro ordered the total integration of Blytheville schools.

[5] The assumed course of study at Blytheville High School is the Smart Core curriculum developed by the Arkansas Department of Education.

Students are engaged in regular and Advanced Placement (AP) coursework and exams prior to graduation, with the opportunity for qualified students to be named honor graduates based on grade point average and additional coursework above minimum requirements.

Blytheville High School is a charter member and has been accredited since 1924 by AdvancED (formerly North Central Association).