[1] Similarly to other single-stranded RNA viruses, the genome of BRSV has a high mutation rate, which results in great antigenetic variation.

[1] Pasteurella multocida, a common commensal of the nasopharynx of cattle, appears to be the main bacterial agent in BRSV-related bovine respiratory disease (BRD).

Anti-inflammatory drugs may be required to reduce fever and inflammation, which may increase the affected animal's food and water intake.

Non-steroidal anti-inflammatory drugs (NSAIDs) are preferred to corticosteroids due to the latter's immunosuppressive effects.

[2] While commercial BRSV vaccines are available, appropriate biosecurity measures and animal husbandry may be sufficient to prevent spread of disease.