Brassinosteroid insensitive-1

[1][2] It plays very important roles in plant development, especially in the control of cell elongation and for the tolerance of environmental stresses.

The RLCKs transduce this signal to downstream components, which ultimately results in the activation or de-activation of several transcription factors.

[5] In the model plant species Arabidopsis thaliana, BRI1 acts alongside two homologous proteins, known as BRI1-LIKE1 (BRL1) and BRL3.

[2] The function of BRL1 and BRL3 appears to be restricted to the development of the vasculature system, but even in this context, BRI1 plays a more dominant role.

[10] Recently it was suggested that BRI1 and FLS2 localize to different 'nano-domains' on the cell membrane and it is this spatial separation that accounts for their very different signal outputs.