The railway eventually moved to an elevated viaduct, leaving only the eastern section of the street today.

Going east, both sides of the street are lined with late 20th-century or early 21st century mid-rise and high-rise condominium projects.

Further to the east, along the north side, are older industrial buildings, such as the Greey's Toronto Mill Furnishing Works Factory at #70, which have been repurposed into commercial space.

The St. Lawrence Recreation Centre is located along the north side of the street, east of Sherbourne, next to Market Lane Public School.

On the north-west corner is the Berkeley Castle, the former 1871 Toronto Knitting & Yarn Factory, repurposed as commercial space.

[2] Ostensibly for carriages and carts, the roadway eventually became primarily the route for rail lines in the central core.

[3] The project was the start of the railways taking over the entire Esplanade to the west of Yonge Street, and almost all of the harbour area.

[5] The Great Western Railway built its rail station at the intersection of Yonge Street and The Esplanade.

After the viaduct was built and passenger rail operations moved to the Union Station to the west, the building was converted to a freight office, then to the Toronto Wholesale Fruit Market.