Using cytoarchitectonics, BA 22 is located in the superior temporal gyrus which separates it from the primary and secondary auditory cortex.

[3] Patients diagnosed with Wernicke's aphasia are shown to have normal intonation and rate of speech, however have difficulty understanding different words of a language.

Many individuals have poor awareness when making errors in speech, but are typically able to produce normal sentence structures when speaking.

These difficulties are shown at a lexical level, for example patients often struggle with naming figures due to accessing words from the lexicon.

[6] Brodmann areas are based on cytoarchitectonic parcellation using numbering associated with locations in the brain to illustrate functional activity.