She made one voyage for the British East India Company (EIC), and two transporting convicts to Australia.

First convict voyage (1823–1824): Under the command of Captain Charles Motley she sailed from The Downs, England to Hobart and Sydney.

[6] AAC voyage (1825): The newly-founded Australian Agricultural Company chartered two ships, Brothers and York,[7] to bring skilled workmen and farm animals to New South Wales.

Brothers, under the command of Captain Moseley [sic][8] and with 370 sheep and 11 horses aboard, sailed in company with York from Cowes, Isle of Wight, on 18 June 1825.

[8] Second convict voyage (1826–1827): Captain Motley sailed from Cork, Ireland, on 3 October 1826, bound for Sydney.