Bruce Eliot Maryanoff FRSC (born February 26, 1947, in Philadelphia, Pennsylvania) is an American medicinal and organic chemist.
He is an inventor of topiramate,[2] a unique sugar sulfamate drug, which has been marketed worldwide for the treatment of epilepsy and migraine, attaining annual sales of more than $2 billion.
He made seminal contributions to understanding the stereochemistry and mechanism of the Wittig reaction; adapted the cobalt-catalyzed alkyne trimerization to the synthesis of macrocycles; and devised novel peptides that undergo self-assembly to mimic native collagen structurally and functionally.
He is an inventor on 100 issued U.S. patents, has presented over 185 invited lectures worldwide, and mentored 11 postdoctoral associates.
Maryanoff organized and edited a special memorial issue of the Journal of Medicinal Chemistry to honor the memory of Dr. Paul Janssen (2005)[5] and has served on numerous editorial advisory boards for scientific journals and research grant review committees.