Buffalo Creek is a tributary of the Monongahela River, 30.2 miles (48.6 km) long,[3] in northern West Virginia, in the United States.

Via the Monongahela and Ohio rivers, it is part of the watershed of the Mississippi River, draining an area of 125 square miles (320 km2)[4] on the unglaciated portion of the Allegheny Plateau.

Buffalo Creek rises near Marion County's western boundary, near the community of Brink, and flows generally eastward through the communities of Logansport, Mannington, Rachel, Farmington, Pine Grove, and Barrackville to Fairmont, where it flows into the Monongahela River from the west.

[5] According to the West Virginia Department of Environmental Protection, approximately 84% of the Buffalo Creek watershed is forested, mostly deciduous.

[4] At the United States Geological Survey's stream gauge at Barrackville, 4.4 miles (7.1 km) upstream of the creek's mouth, the annual mean flow of the river between 1907 and 2012 was 169 cubic feet per second (5 m³/s).