[citation needed] The north side of the right-of-way on the street's eastern half through Mississauga is unusually wide as the result of being reserved for either a light rail transit line, and later as a potential route segment of the proposed GO-ALRT network, neither of which were built.

[1][2] The reserve was converted into a bicycle trail,[3] with another transit facility (the Mississauga Transitway) being constructed along the Highway 403 corridor farther north instead.

At Hurontario Street, it passes by the iconic Absolute World condominium towers, enters Mississauga City Centre, and changes to a West designation.

Continuing west past the city centre area, it traverses a mixed commercial and residential zone, before crossing over the wide Credit River valley on a high-level bridge, and entering the leafy Erin Mills district.

[10] West of Sixth Line it rejoins William Halton Parkway as the latter roads swings in from the northeast, widening to four lanes as it defaults into and becomes Burnhamthorpe west of that point,[11] although project documentation suggests this section of Burnhamthorpe Road may be renamed William Halton Parkway after the project is completed.

[13] MiWay In Mississauga, MiWay Route 26 Burnhamthorpe operates from the South Common Centre (located just west of Erin Mills Parkway), to Islington station in Toronto, serving the Mississauga City Centre Transit Terminal and Kipling Bus Terminal at Kipling station en route.

[16] Burnhamthorpe Road was a relatively minor artery through Etobicoke (previously a separate city within the former Metropolitan Toronto) until traffic increased due to the growth of Mississauga in the 1970's and 80's.

The councils of both cities got involved and the TTC eventually banned MiWay buses from using the bus bays at the subway station.