Larger part of the municipal territory lies in a flat landscape of the Lower Morava Valley.

The northern hilly part lies in the Kyjov Hills and include the highest point of Bzenec, Horní hory at 292 m (958 ft) above sea level.

The first written mention of Bzenec is from 1015, when the local Businc Castle was conquered by Duke Oldřich.

[2] The original castle on the hill above the town was badly damaged during the Hussite Wars and demolished in the late 15th century.

The Jews were permitted to own vineyards, which, together with the town's convenient location on the trade route, were the reasons why they settled here.

[5][6] When the estate was owned by Count Erdmann Kryštof Pruskovský of Pruskov, the castle was rebuilt in the Baroque style according to the design of Domenico Martinelli in 1709–1710.

As a result, the count became very indebted, which eventually led to his suicide, and the second floor of the castle remained unfinished.

Due to its location, the chapel was struck several times by lightning, then it was destroyed during World War II.