[5] Some older literature mention a similar protein called "CD3 eta" in mice.

The encoded protein is 164 amino acids long with a predicted weight of 18.696 kiloDaltons.

The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Low expression of the antigen results in impaired immune response.

Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.