195253883ENSG00000143126ENSMUSG00000068740Q9HCU4Q9R0M0NM_001408NM_001004177NM_017392NP_001399NP_001004177NP_059088Cadherin EGF LAG seven-pass G-type receptor 2 is a protein that in humans is encoded by the CELSR2 gene.

[5][6] The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily.

The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins.

It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions.

[6] This article incorporates text from the United States National Library of Medicine, which is in the public domain.