[5] This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes.

The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.

This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital.

The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide.

Inhibitors of CYP2B6 can be classified by their potency, such as: Moderate: Unspecified potency This article incorporates text from the United States National Library of Medicine, which is in the public domain.