Cafestol is a diterpenoid molecule present in coffee beans.

It is one of the compounds that may be responsible for proposed biological and pharmacological effects of coffee.

[1] A typical bean of Coffea arabica contains about 0.4% to 0.7% cafestol by weight.

[6] Cafestol has also shown anticarcinogenic properties in rats.

[7] Cafestol also has neuroprotective effects in a Drosophila fruit fly model of Parkinson's disease.