From U.S. Route 395, SR 167 runs along Pole Line Road north of Mono Lake eastward to the Nevada state line where it meets Nevada State Route 359.

The route continues in a straight line through a barren landscape in Mono County where it intersects Dobie Meadows Road.

SR 167 meets its eastern terminus at the Nevada state line.

The road continues as Nevada State Route 359 through Mineral County.

[7] Except where prefixed with a letter, postmiles were measured on the road as it was in 1964, based on the alignment that existed at the time, and do not necessarily reflect current mileage.