Callicarpenal is a terpenoid that has been isolated from plants of the genus Callicarpa (beautyberry).
[1] It acts as an insect repellent against mosquitoes (Aedes aegypti and Anopheles stephensi) and fire ants.
[1][2] It also has activity against ticks (Ixodes scapularis and Amblyomma americanum).
[3] In comparison to the most commonly used insect repellent, DEET, callicarpenal is only about 21% less effective at preventing mosquito bites.
[4] Callicarpenal was discovered by scientists at the United States Department of Agriculture's Agricultural Research Service who were inspired by reports that Callicarpa americana (American beautyberry) was used as a folk remedy to prevent mosquito bites.