[2] In the Aonekko ʾaʾien language of the Aonikenk people, the term kamusu (rendered as "Camusu" in Spanish orthography) means "tall waving grass", while aike means "settlement" or "camp".

The name therefore can be translated as "camp by the tall waving grass"[3] The community was established by decree on 11 January 1898 by President José Evaristo Uriburu, wherein the local Aonikenk community were granted a 50 thousand-hectare territory in what was their ancestral land.

The territory was reduced to 30 thousand hectares during the government of President Juan Domingo Perón.

According to the 1966−1968 National Indigenous Census, the community counted with 44 Aonikenk inhabitants, 24 of which spoke Aonekko ʾaʾien.

[6] Camusu Aike was the birthplace of the last fluent speaker of the Aonekko ʾaʾien language, Dora Manchado (1934−2019).