Also in 1987, at the age of 11, Cameron began the most prominent role of her career on the ensemble sitcom Full House, as Donna Jo "D.J."

Cameron hosted the Nickelodeon Kids' Choice Awards in 1990 with Full House co-star Dave Coulier and David Faustino, and again in 1994 with Joey Lawrence and Marc Weiner.

The following year, she co-starred with Randy Travis in The Wager and starred with Tom Arnold in the television movie Moonlight and Mistletoe for the Hallmark Channel in 2008.

[4] On March 4, 2014, it was announced that Bure would compete on season 18 of Dancing with the Stars, partnering with Mark Ballas.

[8] On December 8, 2016, Bure announced that she was leaving The View due to commitment clashes between Fuller House and Hallmark Channel projects and family life.

[13] Bure served as the host of the 26th annual Movieguide Awards for the network on February 8, 2019, along with her daughter Natasha.

[16][17] In a November 2022 interview with The Wall Street Journal, Bure stated that she had left Hallmark because it was a "completely different network than when I started", and wanted to "tell stories that have more meaning and purpose and depth behind them"—including those with stronger faith-based themes (albeit not being "off-putting to the unbeliever or someone who shares a different faith").

"[16][17] Bure's remarks were believed to be an allusion to a trend towards progressive themes, including recognition of the LGBT community, in Hallmark Channel productions.

Abbott left Hallmark Channel in early 2020, shortly after it faced criticism for briefly pulling a Zola.com commercial depicting a lesbian couple.

"[18][19][20] Of Bure's implication that Great American Media productions would never depict same-sex couples, Abbott stated to the Wall Street Journal, "It's certainly the year 2022, so we're aware of the trends.

[24] In a September 2015 interview, Bure revealed that Dancing Through Life discloses more personal issues than her first two books.

[25] In an April 2018 interview, Bure shared that Kind Is the New Classy conveyed the idea of staying centered and practicing graciousness towards others.

[27][29] Their daughter Natasha competed in season 11 of The Voice at the age of 18[30] and played the younger version of her mother's lead character in the final Aurora Teagarden Mystery.