Cane Creek is a 5.10 mi (8.21 km) long 3rd order tributary to the Hyco River in Person County, North Carolina.

According to the Geographic Names Information System, it has also been known historically as:[1] Cane Creek rises in a pond about 0.25 miles southeast of Semora, North Carolina in Caswell County, and then flows northeast into Person County to join the Hyco River about 1.5 miles west of McGehee Mills.

[2] Cane Creek drains 8.25 square miles (21.4 km2) of area, receives about 46.0 in/year of precipitation, has a wetness index of 411.27, and is about 54% forested.

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