Hyco Lake is a reservoir in Person and Caswell counties, North Carolina.

It runs through the following municipalities: Semora, Leasburg, and the city of Roxboro located about ten miles (16 km) from the lake.

Duke Energy Progress owns the land surrounding the lake up to the 420-foot (130 m) above-sea-level mark.

The lake covers 3,750 acres (1,520 ha), containing about 25 billion US gallons (95,000,000 m3) of water, with 120 miles (190 km) of shoreline.

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