The brewery was founded in 1900 by Paul Cantillon, whose father was also a brewer, and his wife, Marie Troch.

[1] As of 2011[update], the owner is Jean-Pierre van Roy, the fourth-generation brewer at Cantillon.

[1][4] In 2014, van Roy announced that the brewery would be acquiring more maturation space, effectively doubling production by 2016–17.

[6] In the traditional lambic style, beers, with a mash bill of 2/3 malted barley and 1/3 unmalted wheat,[1] are spontaneously fermented in open topped attic mounted vats called coolships, aged in oak or chestnut, blended (from different batches and ages), bottled, and then bottle conditioned for a year.

Half of the brewery's production is gueuze; once a year a batch of kriek is made.