Cardenas Butte is a 6,281-foot-elevation summit located in the eastern Grand Canyon, in Coconino County of northern Arizona, Southwestern United States.

Cardenas Butte is named for García López de Cárdenas, the first European to see the Grand Canyon.

At the west, Escalante is separated by a ridge saddle (the drainage southeast into Upper Tanner Canyon).

Its small spire is a surviving cliff-former unit of the Supai Group, the cliff and shelf of the Esplanade Sandstone.

A small amount of debris-remainder may survive on the surface of the prominence-shelf, the slope-former Hermit Shale.