Carlisle is a census-designated place (CDP) in Sequoyah County, Oklahoma, United States.

It is part of the Fort Smith, Arkansas-Oklahoma Metropolitan Statistical Area.

[3] As of the census[5] of 2000, there were 649 people, 233 households, and 178 families residing in the CDP.

There were 260 housing units at an average density of 9.9 per square mile (3.8/km2).

18.5% of all households were made up of individuals, and 7.7% had someone living alone who was 65 years of age or older.